{"id":60382,"date":"2020-10-27T12:24:28","date_gmt":"2020-10-27T10:24:28","guid":{"rendered":"https:\/\/www.csregypt.com\/?p=60382"},"modified":"2020-10-27T12:24:28","modified_gmt":"2020-10-27T10:24:28","slug":"oxford-covid-vaccine-works-in-all-ages-trials-suggest","status":"publish","type":"post","link":"https:\/\/csregypt.com\/en\/oxford-covid-vaccine-works-in-all-ages-trials-suggest\/","title":{"rendered":"Oxford Covid vaccine works in all ages, trials suggest"},"content":{"rendered":"<p dir=\"ltr\" style=\"text-align: left;\">One of the world\u2019s leading Covid-19 experimental vaccines produces an immune response in both older and young adults, raising hopes of a path out of the gloom and economic destruction wrought by the novel coronavirus.<\/p>\n<p dir=\"ltr\" style=\"text-align: left;\">The vaccine, developed by the\u00a0<a class=\"u-underline\" href=\"https:\/\/www.theguardian.com\/education\/oxforduniversity\" data-link-name=\"auto-linked-tag\" data-component=\"auto-linked-tag\">University of Oxford<\/a>, also triggers lower adverse responses among elderly people, said the British drug maker AstraZeneca, which is helping to manufacture the vaccine, on Monday.<\/p>\n<p dir=\"ltr\" style=\"text-align: left;\">A vaccine that works is seen as a game-changer in the battle against coronavirus, which has killed more than 1.15 million people, shuttered swathes of the global economy and turned normal life upside down for billions of people.<\/p>\n<aside class=\"element element-rich-link element--thumbnail element-rich-link--upgraded\" dir=\"ltr\" data-component=\"rich-link\" data-link-name=\"rich-link-2 | 1\">\n<div class=\"rich-link tone-news--item rich-link--pillar-news\">\n<div class=\"rich-link__container\">\n<div class=\"rich-link__image-container u-responsive-ratio\">\u201cIt is encouraging to see immunogenicity responses were similar between older and younger adults and that reactogenicity was lower in older adults, where the Covid-19 disease severity is higher,\u201d an <a class=\"u-underline\" href=\"https:\/\/www.theguardian.com\/business\/astrazeneca\" data-link-name=\"auto-linked-tag\" data-component=\"auto-linked-tag\">AstraZeneca<\/a>\u00a0spokesman said.<\/div>\n<\/div>\n<\/div>\n<\/aside>\n<p dir=\"ltr\" style=\"text-align: left;\">\u201cThe results further build the body of evidence for the safety and immunogenicity of AZD1222,\u201d the spokesman said, referring to the technical name of the vaccine.<\/p>\n<p dir=\"ltr\" style=\"text-align: left;\">AstraZeneca did not provide detail of the data behind the statement or say when it would publish eagerly awaited late-stage phase 3 trial data, which would show whether the vaccine works well enough in large-scale trials for it to be approved.<\/p>\n<p dir=\"ltr\" style=\"text-align: left;\">The vaccine is expected to be one of the first from big pharma to secure regulatory approval, along with one from Pfizer and BioNTech.<\/p>\n<p dir=\"ltr\" style=\"text-align: left;\">The news that older people get an immune response from the vaccine is positive because the immune system weakens with age and older people are those most at risk of dying from the virus.<\/p>\n<p dir=\"ltr\" style=\"text-align: left;\">If it works, a vaccine would allow the world to return to some measure of normality after the pandemic.<\/p>\n<p dir=\"ltr\" style=\"text-align: left;\">The British health secretary, Matt Hancock, said a vaccine was not yet ready but he was preparing logistics for a\u00a0<a class=\"u-underline\" href=\"https:\/\/www.theguardian.com\/world\/2020\/oct\/19\/covid-vaccine-will-not-be-available-in-uk-until-spring-says-vallance\" data-link-name=\"in body link\">possible roll<\/a><a class=\"u-underline\" href=\"https:\/\/www.theguardian.com\/world\/2020\/oct\/19\/covid-vaccine-will-not-be-available-in-uk-until-spring-says-vallance\" data-link-name=\"in body link\">out<\/a>, mostly in the first half of 2021.<\/p>\n<p dir=\"ltr\" style=\"text-align: left;\">Asked if some people could receive a vaccine this year, he told the BBC: \u201cI don\u2019t rule that out but that is not my central expectation.\u201d<\/p>\n<p dir=\"ltr\" style=\"text-align: left;\">Immunogenicity blood tests carried out on a subset of older participants echo data released in July that showed the vaccine generated \u201crobust immune responses\u201d in a group of healthy adults aged between 18 and 55, the Financial Times reported earlier.<\/p>\n<p dir=\"ltr\" style=\"text-align: left;\">\u201cWe need to see the data before concluding that the responses were \u2018similar\u2019,\u201d said Stephen Evans, a professor of pharmacoepidemiology at the London School of Hygiene &amp; Tropical Medicine.<\/p>\n<p dir=\"ltr\" style=\"text-align: left;\">He said that reactogenecity \u2013 the common side-effects of vaccines such as soreness and redness of the arm \u2013 was \u201coften, but not always\u201d associated with a vaccine\u2019s immunogenicity.<\/p>\n<p dir=\"ltr\" style=\"text-align: left;\">\u201cStudies carried out in the first stage of development of a vaccine will result in choosing a dose that does not cause too much reactogenicity,\u201d he said.<\/p>\n<p dir=\"ltr\" style=\"text-align: left;\">AstraZeneca has signed several supply and manufacturing deals with companies and governments around the world as it gets closer to reporting early results of the late-stage clinical trial.<\/p>\n<p dir=\"ltr\" style=\"text-align: left;\">It resumed the US trial of the experimental vaccine after approval by US regulators, the company said on Friday.<\/p>\n<p dir=\"ltr\" style=\"text-align: left;\">Staff at a London hospital trust have been told to be ready to receive the first batches of the Oxford-AstraZeneca vaccine, the Sun reported on Monday.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>One of the world\u2019s leading Covid-19 experimental vaccines produces an immune response in both older and young adults, raising hopes of a path out of the gloom and economic destruction wrought by the novel coronavirus. The vaccine, developed by the\u00a0University of Oxford, also triggers lower adverse responses among elderly people, said the British drug maker [&hellip;]<\/p>\n","protected":false},"author":410,"featured_media":60383,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[6031,984],"tags":[7693,9571],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v22.6 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Oxford Covid vaccine works in all ages, trials suggest - Csr Egypt<\/title>\n<meta name=\"description\" content=\"One of the world\u2019s leading Covid-19 experimental vaccines produces an immune response in both older and young adults\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/csregypt.com\/en\/oxford-covid-vaccine-works-in-all-ages-trials-suggest\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Oxford Covid vaccine works in all ages, trials suggest - 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