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European Commission authorizes AstaZeneca’s COVID-19 vaccine
The European Commission has granted a conditional marketing authorization (CMA) for the COVID‑19 vaccine developed by AstraZeneca, the third COVID-19 vaccine authorized in the EU.
This authorization follows a positive scientific recommendation based on a thorough assessment of the safety, effectiveness and quality of the vaccine by the European Medicines Agency (EMA) and is endorsed by the Member States.
The President of the European Commission, Ursula von der Leyen, said: “Securing safe vaccines for Europeans is our utmost priority. With the AstraZeneca vaccine now authorized, 400 million additional doses will be available in Europe. I expect the company to deliver these doses as agreed, so that Europeans can be vaccinated as soon as possible. We will continue doing all we can to secure more vaccines for Europeans, our neighbors and our partners worldwide.”
Stella Kyriakides, Commissioner for Health and Food Safety, said: “With this newly authorized vaccine, our portfolio continues to take shape. Our EU Vaccines Strategy has always aimed to have a vaccine portfolio that is broad and diverse, with different technologies used, to maximize our chances of providing safe and effective vaccines to citizens as soon as possible. The European Medicines Agency’s authorization today is another step towards delivering on this promise. The Commission continues to work around the clock to secure more vaccines for Europe and our international partners. We are leaving no stone unturned in our fight against this pandemic.”
The AstraZeneca vaccine will be given to adults aged 18 years and older for preventing COVID-19. The vaccine causes the immune system (the body’s natural defences) to produce antibodies and specialized white blood cells that work against the virus, so giving protection against COVID-19. People vaccinated will receive two injections of the AstraZeneca vaccine.
According to EMA, most of the participants in the studies were between 18 and 55 years old. There are not yet enough results in older participants (over 55 years old) to provide a figure for how well the vaccine will work in this group. However, protection is expected, given that an immune response is seen in this age group and based on experience with other vaccines; as there is reliable information on safety in this population, EMA’s scientific experts considered that the vaccine can be used in older adults.
The AstraZeneca vaccine is based on an adenovirus, a harmless virus which delivers the ‘instructions’ from the virus that causes COVID-19.This allows the body’s own cells to make the protein unique to the COVID-19 virus. The person’s immune system recognizes that this unique protein should not be in the body and responds by producing natural defenses against infection by COVID-19.
According to the contract signed with the European Commission on 27 August 2020, AstraZeneca will deliver the total amount of 400 million doses throughout 2021. These will add to the 600 million doses of the vaccine by BioNTech-Pfizer and the 160 million doses of the vaccine by Moderna.
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